BMS-241027, also known as Epothilone D, is a microtubule stabilizing agent that also has effects on tau protein in animal models of Alzheimer’s disease. The purpose of this study is to evaluate whether BMS-241027 is safe and well-tolerated in subjects with Alzheimer’s disease.

The purpose of this study is to assess the safety, tolerability, and efficacy of ACC-001, an investigational active immunization, in patients with mild to moderate Alzheimer's disease. ACC-001 is a protein designed to act like a vaccine to stimulate the body to produce antibodies to amyloid protein (the presumed cause of Alzheimer's disease) and help remove amyloid protein from the brain. This study is now closed to enrollment, but follow-up is continuing for the current participants.

The study hypothesizes that donepezil will have a positive impact on brain blood flow deficits in subjects with memory deficits and/or mild dementia and that improvements in brain blood flow will be accompanied by improvements in memory.

The purpose of this study is to evaluate the efficacy and safety of Crenezumab, an amyloid antibody, in patients with mild to moderate Alzheimer's disease.